Cortisol & Female Hormones


Many factors contribute to low Thyroid function and a Saliva Cortisol & Female Hormones test may help a lot to identity underlying and causes.

In the saliva cortisol test four samples of saliva are taken over one day, 8am, 12noon, 4pm & 8pm.  The results provide indications on the individuals stress response and adrenal imbalances. Besides low thyroid function other indicators adrenal dysfunction are anxiety, headaches, poor concentration or ‘brain fog’, fatigue, lethary, salt cravings, mild depression, lack of stamina, sexual dysfunction, irregular sleep patterns.

In addition to the Cortisol test, a test between 10pm and midnight for Melatonin for sleep is advantageous.


Female Hormones

Balancing all Female hormones is essential to the recovery of the Thyroid function and include Oestrogen, Progesterone & Testosterone.  Oestrogen can be then further sub-divided into E1, E2 and E3.

This is a simple Female Hormone saliva test, preferably collected on Day 21 of cycling women, and anytime for the menopausal woman.

Estrone (E1) is made by the conversion of androgens (aromatisation) and from Estradiol (E2).  This has consierable oestrogenic activity although it is less potent than E2.

Estradiol (E2) is the most active and potent estrogen activity being about 10 times more potent than E1 and about 80 times more potent than E3 in its oestrogenic effect.  It is the predominant estrogen during reproductive years both in terms of serum levels and oestrogenic activity. During menopause E1 is the predominant circulating oestrogen and during pregnancy E3 is the predominant circulating oestrogen.

E1 and E2 are interchangable, with the conversion of E2 to E1 being favoured.

Estradiol (E2) is further converted into two types metabolites by araomatise conversion.  Only one type of metabolite can be made at a time; 20hyrdoryxoestrone described as good or protective and 16-hyrodxyoestronge can be described as bad or having stronger growth potential.

Estriol (E3) is a metabolite of E1 and E2 and is the weakest oestrone being 80% less than Estradiol (E2)



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